Category:
Medical Studies
Gefitinib Followed By Surgery in Treating Women With Ductal Carcinoma In Situ of the Breast
RATIONALE: Gefitinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. It is not yet known whether surgery is more effective with or without gefitinib in treating ductal carcinoma in situ.
PURPOSE: This randomized phase II trial is studying how well giving gefitinib together with surgery works compared to surgery alone in treating women with ductal carcinoma in situ of the breast.
|
|
Category:
Medical Studies
Breast Ducts: A New Site for Cancer Treatment?
BALTIMORE, Jan. 25 (AScribe Newswire) -- Johns Hopkins Kimmel Cancer Center researchers are studying whether delivering chemotherapy drugs directly to breast "plumbing" might make treatment of early breast cancer easier on the patient and at least as good as surgery or radiation.
A report on successful tests of intraductal therapy in rats and mice published in the January 15 issue of Cancer Research has paved the way for one of the first preliminary clinical trials in women with breast cancer, currently under way in women with breast cancer scheduled for a mastectomy at Johns Hopkins.
|
2006/01/25 |
Category:
Definition & Diagnosis
Breast Reconstruction
Breast reconstruction (surgery to rebuild a breast's shape) is often an option after mastectomy. Some health insurance plans pay for all or part of the cost of breast reconstruction and, also, for surgery to the other breast so that both breasts are about the same shape and size.
|
|
Category:
Miscellaneous
Cancer and Complementary and Alternative Medicine
# Complementary and alternative medicine (CAM) is a group of diverse medical and health care systems, practices, and products that are not part of conventional medicine.
The same scientific evaluation that is used to assess conventional cancer treatments should be used to assess CAM therapies.
|
|
Category:
Medical Studies
The Clinical Significance of Cytokeratin-Positive Cells in Lymph Nodes at the Time of Mastectomy Fro
. . . Conclusions: Epithelial cells may be present in the lymph nodes draining a site of recent breast biopsy in the absence of invasive carcinoma, indicating that these are an artifact of recent surgery and not of micrometastatic disease.
|
|
Category:
Diet & Exercise
But Will it (Running) Stop Cancer
. . . There is less agreement on whether it can also prevent cancer. But for two types, the evidence is promising: breast cancer and cancer of the colon. Other cancers have not been studied, or the studies that have been done have yielded little evidence that exercise can help.
|
|
Category:
Medical Studies
Vaccines for D.C.I.S.
A cancer vaccine strategy may be the ideal intervention to treat DCIS. If carefully designed, a vaccine treatment is likely to be very safe and easy to take, unlike existing therapies wrought with side effects such as nausea and hair loss. In addition, patients with DCIS are more likely to respond to an anticancer vaccine than patients with advanced breast cancer, both because the amount of cancer in their bodies is far less, and because patients with DCIS generally have healthy immune systems.
|
|
Category:
Diet & Exercise
Garlic and Cancer Prevention: Questions and Answers
A host of studies provide compelling evidence that garlic and its organic allyl sulfur components are effective inhibitors of the cancer process. These studies reveal that the benefits of garlic are not limited to a specific species, to a particular tissue, or to a specific carcinogen. Of 37 observational studies in humans using garlic and related allyl sulfur components, 28 studies showed some cancer preventive effect.
|
|
Category:
Medical Studies
Pathological validation and significance of micrometastasis in
Abstract: In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy
in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The
consequences of missing sentinel node micrometastasis can directly influence treatment strategies,
and this screening therefore has to be performed with more attention than usual. There is presently
great diversity in the histopathological work-up of sentinel nodes, with many centres employing
additional techniques such as immunohistochemistry, reverse transcription polymerase chain
reaction or flow cytometry in addition to routine haematoxylin and eosin staining. In this review, we
address the pathological validation and significance of micrometastasis in sentinel node biopsy in
primary breast cancer.
|
|
Category:
Miscellaneous
Alternative/Complementary Medicine
An "alternative" therapy is a treatment that is used in place of traditional medicine. A "complementary" therapy is a treatment that is used as a supplement to traditional medicine. Alternative and complementary medicines have become increasingly popular in recent years. According to the National Institutes of Health’s National Center for Alternative and Complementary Medicine (NCCAM), Americans spent more than $27 billion on alternative or complementary therapies in 1997.
|
|
Category:
Definition & Diagnosis
DCIS: Treating a Pre-cancer
As more American women are screened for breast cancer with mammograms, doctors are seeing more of a condition called ductal carcinoma in situ (DCIS). Sometimes called a pre-cancer and sometimes Stage 0 breast cancer, DCIS is a non-invasive lesion that is confined within the lining of the milk ducts of the breast that is more benign than a cancerous tumor in that it does not have the ability to invade other parts of the body.
|
|
Category:
Medical Studies
A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Ea
Background In hormone-dependent breast cancer, five years of postoperative tamoxifen therapy — but not tamoxifen therapy of longer duration — prolongs disease-free and overall survival. The aromatase inhibitor letrozole, by suppressing estrogen production, might improve the outcome after the discontinuation of tamoxifen therapy.
|
|
Category:
Medical Studies
Sentinel lymph node biopsy: is it indicated in patients with high-risk ductal carcinoma-in-situ and
BACKGROUND: Axillary lymph node status is the strongest prognostic indicator of survival for women with breast cancer. The purpose of this study was to determine the incidence of sentinel node metastases in patients with high-risk ductal carcinoma-in-situ (DCIS) and DCIS with microinvasion (DCISM).
|
|
Category:
Medical Studies
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson C
BACKGROUND: The authors examined the published evidence on the use of aromatase inhibitors (AIs) in the adjuvant setting in postmenopausal, hormone receptor-positive patients, and they provide recommendations for clinical management in 3 different situations: newly diagnosed women, women who have already received tamoxifen for 2-3 years, and women who have completed 5-years of tamoxifen and are disease free.
|
|
Category:
Medical Studies
A retrospective review of wide excision alone for ductal carcinoma in situ (DCIS) of the breast
Background: The standard treatment for ductal carcinoma in situ (DCIS) of the breast today is wide excision (WE) followed by radiotherapy.
|
2004/07/15 |
Category:
Definition & Diagnosis
The National Coalition For Cancer Survivorship
Breast cancer is a common malignancy, with almost 200,000 new cases diagnosed in the United States each year. The disease occurs most frequently in women and rarely, in men. The breasts are glands that produce and release milk in women in association with pregnancy. Breast cancer develops from cells in the breast.
|
|
Category:
Miscellaneous
Journal of the National Cancer Institute
Cancer Publication
|
|
Category:
Miscellaneous
PubMed
Cancer Site
|
|
Category:
Diet & Exercise
Annals of Surgical Oconlolgy
Cancer Site
|
|
Category:
Medical Studies
False Positive Lymph Nodes in Breast Carcinoma. Do They Exist?
CK positive cells in SLNs may represent the result of transport of displaced cells originating in an intraductal papilloma. Positive IHC results in SLNs should be interpreted with great care, particularly in cases of pure DCIS to avoid automatically concluding that such cells represent metastasis. Sentinel lymph nodes in breast carcinoma can be falsely positive.
|
|